Table 4.
The relationship between p73 protein expression and clinicopathological characteristics in 383 colorectal cancer patients n (%)
| Clinicopathological characteristics | No. of cases |
p73 protein expression |
P | |
| Positive | Negative | |||
| (n = 252) | (n = 131) | |||
| Age (yr) | 0.45 | |||
| < 60 | 166 | 113 (68.1) | 53 (31.9) | |
| ≥ 60 | 217 | 139 (64.1) | 78 (35.9) | |
| Gender | 1.00 | |||
| Male | 203 | 134 (66.0) | 69 (34.0) | |
| Female | 180 | 118 (65.6) | 62 (34.4) | |
| Histological type | 0.19 | |||
| Well | 256 | 169 (66.0) | 87 (34.0) | |
| Moderate | 102 | 64 (62.7) | 38 (37.3) | |
| Poorly | 12 | 7 (58.3) | 5 (41.7) | |
| Mucinous | 13 | 12 (92.3) | 1 (7.7) | |
| Invasion depth | 0.003 | |||
| Mucosa | 3 | 1 (33.3) | 2 (66.7) | |
| Submucosa | 9 | 9 (100) | 0 (0) | |
| Muscle | 47 | 39 (83.0) | 8 (17.0) | |
| Subserosa | 324 | 203 (62.7) | 121 (37.3) | |
| Lymph node metastasis | 0.67 | |||
| Positive | 175 | 113 (64.6) | 62 (35.4) | |
| Negative | 208 | 139 (66.8) | 69 (33.2) | |
| Dukes’ stage | 0.06 | |||
| A | 3 | 1 (33.3) | 2 (66.7) | |
| B1 | 43 | 36 (83.7) | 7 (16.3) | |
| B2 | 162 | 102 (63.0) | 60 (37.0) | |
| C1 | 13 | 10 (76.9) | 3 (23.1) | |
| C2 | 148 | 92 (62.2) | 56 (37.8) | |
| D | 14 | 11 (78.6) | 3 (21.4) | |