Table 1.
Mice | ALT (IU/L) | AST (IU/L) | ALB+/Y-chromosome+ cells | |||||||
---|---|---|---|---|---|---|---|---|---|---|
0 d | 3 d | 7 d | 21 d | 0 d | 3 d | 7 d | 21 d | 14 d | 21 d | |
G1 | 37.9 ± 7.2 | 418.3 ± 49.8† | 228.3 ± 32.7* | 78.3 ± 5.7* | 31.1 ± 6.9 | 398.3 ± 42.8† | 256.3 ± 36.8* | 89.2 ± 6.4* | _ | +# |
G2 | 36.4 ± 6.7 | 434.5 ± 53.8 | 378.6 ± 51.2 | 169.3 ± 34.7 | 29.8 ± 6.3 | 402.5 ± 46.5 | 381.2 ± 50.9 | 209.5 ± 38.4 | _ | _ |
G3 | 38.4 ± 7.1 | 40.9 ± 6.1 | 38.3 ± 6.8 | 42.3 ± 6.7 | 30.7 ± 6.5 | 31.7 ± 6.4 | 30.8 ± 6.9 | 31.1 ± 6.5 | _ | _ |
Data are means ± SD (n = 10). *P < 0.05 compared with the G2 mice; †P > 0.05 compared with the G2 mice. #Human ALB+/Y chromosome+ hepatocyte-like cells in the liver of G1 mice. G-CSF, granulocyte colony-stimulating factor; ALB, albumin; ALT, alanine aminotransferase aspartate; AST, aspartate aminotransferase.