Table 2.
Region 1 | Region 2 | Region 3 | Region 4 | P value | |
---|---|---|---|---|---|
(n=265) | (n=253) | (n=185) | (n=160) | ||
Patient characteristics | |||||
- Male (%) | 203 (76.6) | 190 (75.1) | 130 (70.3) | 123 (76.9) | 0.415 |
- Age (years) | 61±13 | 61±13 | 61±13 | 62±12 | 0.931 |
- BMI (kg/m2) | 28.7 (25.5-42.6) | 28.4 (25.0-40.4) | 27.5 (24.5-39.6) | 27.8 (24.7-42.3) | 0.466 |
Risk factors (%) | |||||
- Smoking | 151 (57.0) | 128 (50.8) | 105 (57.1) | 78 (49.1) | 0.239 |
- Hypertension | 102 (38.5) | 86 (34.3) | 68 (37.0) | 51 (32.1) | 0.540 |
- Hyperlipidaemia | 50 (18.9) | 49 (19.4) | 35 (19.0) | 33 (20.8) | 0.969 |
- Family history | 115 (43.4) | 99 (39.3) | 81 (44.0) | 63 (39.6) | 0.658 |
- Diabetes mellitus | 29 (11.0) | 36 (14.3) | 26 (14.1) | 17 (10.7) | 0.533 |
- Prior MI | 24 (9.1) | 34 (13.5) | 16 (8.7) | 16 (10.1) | 0.304 |
- Prior PCI | 21 (8.0) | 22 (8.7) | 10 (5.4) | 9 (5.7) | 0.471 |
- CABG in past | 6 (2.3) | 8 (3.2) | 3 (1.6) | 3 (1.9) | 0.724 |
- History of AP | 33 (12.6) | 43 (17.5) | 28 (15.6) | 25 (15.8) | 0.498 |
No. of risk factors | |||||
- 0 | 39 (14.7) | 31 (12.3) | 12 (6.5) | 20 (12.5) | 0.063 |
- 1-2 | 139 (52.5) | 145 (57.3) | 119 (64.3) | 97 (60.6) | 0.076 |
- 3-4 | 73 (27.5) | 63 (24.9) | 45 (24.3) | 37 (23.1) | 0.747 |
- ≥4 | 36 (13.6) | 39 (15.4) | 23 (12.4) | 15 (9.4) | 0.352 |
Medication before MI (%) | |||||
- β-blocker | 67 (25.4) | 45 (18.0) | 41 (22.4) | 27 (17.0) | 0.104 |
- Aspirin | 51 (19.2) | 52 (20.8) | 33 (18.0) | 20 (12.6) | 0.195 |
- Statin | 52 (19.7) | 48 (19.2) | 34 (18.6) | 21 (13.2) | 0.354 |
- ACE inhibitor | 35 (13.2) | 33 (13.2) | 20 (10.9) | 17 (10.7) | 0.779 |
- Ang II antagonist | 15 (5.7)* | 16 (6.4) | 25 (13.7)* | 10 (6.3) | 0.008* |
- Diuretic | 31 (11.7) | 25 (10.0) | 22 (12.0) | 23 (14.5) | 0.598 |
- Calcium antagonist | 30 (11.3) | 25 (10.0) | 21 (11.5) | 15 (9.4) | 0.893 |
Peak troponin T (μg/l) | 3.45 (1.28-7.14) | 2.81 (0.92-6.39) | 3.34 (1.24-6.68) | 3.95 (1.98-7.87) | 0.083 |
Peak CPK (U/l) | 1388 (587-2618) | 997 (448-2165) | 1323 (522-2727) | 1586 (755-3146) | 0.008* |
LVEF 3 months post-MI (%) | 56 (47-64) | 56 (47-64) | 55 (49-63) | 55 (47-63) | 0.887 |
Values expressed as n (%), normally distributed data as mean ± standard deviation, otherwise as median (interquartile range [IQR]: 25th-75th percentile). * p<0.05. ACE=angiotensin-converting enzyme, ANG=angiotensin, AP=angina pectoris, BMI=body mass index, CABG=coronary artery bypass surgery, CPK=creatine phosphokinase, LVEF=left ventricular ejection fraction, MI=myocardial infarction, PCI=percutaneous coronary intervention.