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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Brain Res. 2010 Jul 21;1354:172–178. doi: 10.1016/j.brainres.2010.07.041

Figure 5. HDACIs inhibit MPP+-induced TH+ cell loss.

Figure 5

Cells were treated with MPP+ (SK-N-SH: 100μM MPP+ for 48 hrs; MES 23.5: 50μM MPP+ for 24 hrs) and the number of tyrosine hydroxylase immuno-positive (TH+) cells was determined using a stereological procedure. The number of TH+ cells per well were compared to control wells not receiving MPP+ to determine the % of control. a, α Untreated/Control vs. Untreated/MPP+ p<0.001; b, β Untreated/MPP+ vs. NaB/MPP+ p<0.05; c, γ: Untreated/MPP+ vs. VPA/MPP+ p<0.05; d, δ: Untreated/MPP+ vs. SAHA/MPP+ p< 0.01.