Table 1.
Genotypes, Phenotypes, and the Effects of pH Variation on Growth Rates for C. albicans Strains
| Strain | Genotype | Phenotype | Doubling Time (h)* |
||
|---|---|---|---|---|---|
| pH 6.0 | pH 7.3 | pH 8.0 | |||
| SC531432 | Clinical isolate | Wild-type | 1.17 ± 0.02 | 1.28 ± 0.02 | 1.45 ± 0.01 |
| DAY18528 | ura3Δ::λimm434pHIS1::his1::hisGarg4::URA3::arg4::hisG | Wild-type | 1.54 ± 0.02 | 1.46 ± 0.02 | 1.61 ± 0.06 |
| ura3Δ::λimm434 his1::hisG arg4::hisG | |||||
| DAY2528 | ura3Δ::λimm434pHIS1::his1::hisGarg4::hisG rim101::URA3 | Rim101p-negative | 1.46 ± 0.02 | 1.66 ± 0.01 | 1.71 ± 0.04 |
| ura3Δ::λimm434 his1::hisG arg4::hisG rim101::ARG4 | |||||
| DAY11119 | ura3Δ::λimm434his1::hisG arg4::hisG rim20::ARG4 pRIM101 | Rim20p-negative | 1.50 ± 0.03 | 1.45 ± 0.02 | 1.83 ± 0.03 |
| ura3Δ::λimm434 his1::hisG arg4::hisG rim20::URA3 RIM101 | |||||
| DAY11728 | ura3Δ::λimm434HIS1::his1::hisGarg4::hisGrim8::ARG4 | Rim8p-negative | 1.48 ± 0.02 | 1.46 ± 0.02 | 1.86 ± 0.02 |
| ura3Δ::λimm434 his1::hisG arg4::hisG rim8::URA3 | |||||
| GK08820 | ura3Δ::limm434his1::hisGarg4::hisGrim13::URA3 | Rim13p-negative | 1.44 ± 0.10 | 1.56 ± 0.06 | 1.97 ± 0.03 |
| ura3Δ::limm434 his1::hisG arg4::hisG rim13::ARG4 | |||||
| CAS1035 | Δura3::imm434 Δphr1::hisG | Phr1p-negative | 1.24 ± 0.02 | 1.59 ± 0.02 | 2.00 ± 0.03 |
| Δura3::imm434 Δphr1 | |||||
*
Mean ± SD.