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Computer-modeled 2-D structure. An Als2cr4-translated AA sequence was used to identify transmembrane helices with version 2 of the TMHMM Server. The data were input into TMRPres2D software to create a 2-D model of α-helical or β-barrel transmembrane proteins. Four potential transmembrane domains were identified, in addition to a long amino-terminal tail (226 AAs) and a short carboxyl-terminal tail (30 AAs), which are predicted to reside within the cytoplasm.
