Table 3-b.
Three disease associated metabolites (hippurate, alanine and formate)
| Metabolite | Logistic coefficient (|β|) | Power |
FP rate |
||
|---|---|---|---|---|---|
| Hippurate 1.0 | Alanine 2.0 | Formate 4.0 | |||
| O2PLS Bootstrap | 50/50 | 18% | 12% | 94% | 79.6% |
| 100/100 | 36% | 26% | 100% | 73.2% | |
| 200/200 | 60% | 46% | 100% | 68.8% | |
| O2PLS Permutation | 50/50 | 14% | 8% | 92% | 65.9% |
| 100/100 | 26% | 22% | 100% | 49.8% | |
| 200/200 | 34% | 28% | 100% | 46.9% | |
| T-test Bonferroni | 50/50 | 0% | 0% | 38% | 2.0% |
| 100/100 | 0% | 2% | 100% | 0.5% | |
| 200/200 | 2% | 4% | 100% | 9.3% | |
| T-test exact MWSL | 50/50 | 0% | 0% | 70% | 1.2% |
| 100/100 | 4% | 4% | 100% | 2.5% | |
| 200/200 | 4% | 10% | 100% | 13.5% | |
| T-test general MWSL α′ = 1.5 × 10−6 | 50/50 | 0% | 0% | 54% | 1.0% |
| 100/100 | 0% | 2% | 100% | 1.3% | |
| 200/200 | 4% | 8% | 100% | 11.7% | |