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Specificity fingerprints determined by SAMDI for a) KDAC8, b) SIRT1, c) KDAC2, and d) KDAC3/SMRT. An array of peptides having sequence Ac-GRKAcXZC-NH2 was created, where the X and Z residues are shown on the horizontal and vertical axes, respectively. The degree of deacetylation was determined by SAMDI and is represented by the gray scale bar.
