Fig. 1.

LD in Ashkenazi Jews compared with Europeans. (A) A 1.7-Mb sliding window shifting 100 kb along chromosome 22. (Upper) AJ and Euro populations; (Lower) AJ and EA populations. For each window, the average r² was calculated between all pairs of SNPs within 500 kb of each other. The Insets show the AJ r² minus the Euro or EA r², respectively. (B) The decay of LD across all of the autosomes was assessed by grouping pairs of SNPs according to the distance separating them (0–5 kb, 5–10 kb, …, 495–500 kb) and then plotting the average r² of each bin. (Left) Distances from 0 to 50 kb; (Right) distances from 50 to 500 kb. Note the scales on the y axis are different for the Left and Right.