Table 1.
Pop | LD pruned | SNPs | HET(Exp) | HET(Obs) | F |
AJ | No | 242k | 0.2296 | 0.2298** | −0.0011* |
Euro | No | 242k | 0.2262 | 0.2257 | 0.0022 |
AJ | Yes | 107k | 0.2390 | 0.2394** | −0.0014* |
Euro | Yes | 107k | 0.2363 | 0.2358 | 0.0020 |
AJ | No | 732k | 0.2705 | 0.2714** | −0.0033* |
EA | No | 732k | 0.2696 | 0.2697 | −0.0004 |
AJ | Yes | 207k | 0.2518 | 0.2527** | −0.0038* |
EA | Yes | 207k | 0.2510 | 0.2511 | −0.0005 |
Expected heterozygosity, HET(Exp), observed heterozygosity, HET(Obs), and inbreeding coefficient, F, for the AJ, Euro, and EA populations. One SNP of a pair was pruned out of the dataset if the pair was in high LD, defined as pairwise r2 > 0.5. The shading of rows highlights the AJ population with the corresponding SNP-matched European population.
**P < 1e-40 and *P < 1e-7 for AJ compared with its paired European population (t test).