Fig. 4.

Correlated Ca²⁺ dynamics and discharge patterns of vibration-sensitive neurons. (A) Ca²⁺ imaging with simultaneous electrophysiological recording reveals the difference between V-SA (red traces) and V-RA (blue traces) cells in both adaptation properties and Ca²⁺ dynamics. From the top in each column: Ca²⁺ transients; position of vibration stimuli on the time axis; membrane potential recording (whole-cell); time zoom of above potential recording. (Bottom trace) Profile of vibrational stimulation. (B) Delay between the vibration stimulus onset and Ca²⁺ transient maximum for high frequencies is smaller for V-RA (n = 30; N = 2) than for V-SA neurons (n = 29; N = 2). Asterisks depict significance between delay for V-RA and V-SA neurons for the same frequency of stimulation. ***P < 0.001 (Mann-Whitney test).