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. Author manuscript; available in PMC: 2010 Sep 17.
Published in final edited form as: Toxicol Pathol. 2010 Feb 26;38(3):382–392. doi: 10.1177/0192623310362706

Figure 4.

Figure 4

Ovalbumin (OVA)-induced mucous cell metaplasia. (A–D) Photomicrographs of respiratory epithelium at G5 stained with Alcian Blue (pH 2.5)/Periodic Acid Schiff sequence at 96 hours postchallenge. (A) C57BL/6 sal. (B) CB1/CB2 null sal. (C) C57BL/6 OVA. (D) CB1/CB2 null OVA. (E) Enumeration of AB-PAS+ epithelial cells at 6 and 96 hours postchallenge. (a) p < .05 versus respective saline. (b) p < .05 treatment-matched genotype difference; (c) p < .05 treatment-matched time difference. a = alveoli; aw = airway; e = endothelium; I = interstitium. Arrows indicate positive staining of stored intraepithelial mucosubstances.