Table 3.
Daily Dose (in Micrograms) of Levothyroxine Supplementation
| Group | n | Period 1 | Period 2 | Period 3 | Mean Δ2−1 | Mean Δ3−1 | Mean Δ3−2 |
|---|---|---|---|---|---|---|---|
| A | 32 | 100.3 ± 7.2 | 112.2 ± 8.1 | 109.7 ± 8.4 | 12.3%a | 10.0%a | −7.5% |
| Pattern 1 | 11 | 83.9 ± 10.5 | 88.6 ± 11.2 | 79.6 ± 9.6 | 5.4% | −3.8% | −8.2%a |
| Pattern 2 | 18 | 113.8 ± 10.1 | 130.7 ± 11.8 | 129.3 ± 11.4 | 18.6%a | 17.6%a | 1.5% |
| B | 32 | 93.1 ± 7.5 | 94.3 ± 7.7 | 97.8 ± 7.6 | 1.6% | 8.0% | 5.7% |
Mean percent change in daily levothyroxine dosing between periods: period 2 and period 1 (mean Δ2−1), period 3 and period 1 (mean Δ3−1), and period 3 and period 2 (mean Δ3−2) are indicated. The results are provided in micrograms as mean ± SEM.
a
p < 0.05 (two sided) for both nonparametric tests.