Table 4.

Prediction of Increased Levothyroxine Need

Predictor	Odds ratio	p-Value
Univariate logistic regression results
Age (years)	0.96	0.60
Baseline TSH	2.6	0.10
Baseline levothyroxine	0.98	0.16
Prior pregnancies	0.21	0.17
Supplementation pattern 2	15.7	0.02
Area	1.02	0.08
Multivariate logistic regression
Supplementation pattern 2	62.0	0.005
Baseline levothyroxine	0.97	0.04

Outcome of interest was a 3-month postpartum levothyroxine dose at least 20% over baseline.

Area was the area under the levothyroxine supplementation curve during pregnancy. Pattern 2 was the supplementation pattern during pregnancy such that doses increased in each trimester as described in the text.