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Diagnosis of CLL
| Clonal expansion of abnormal B lymphocytes in PB |
| At least 5 × 109 B lymphocytes/L (5000/μL) |
| Lymphoid cells ≤ 55% atypical/immature |
| Low density of surface Ig (IgM or IgD) with κ or λ light chains |
| B-cell surface antigens (CD19, CD20dim, CD23) |
| CD5 surface antigen |
