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. 2010 Oct 1;33(10):1349–1355. doi: 10.1093/sleep/33.10.1349

Table 2.

Autonomic cardiovascular tests parameters in children with obstructive sleep apnea syndrome (OSAS group) and in healthy children (control group)

OSAS group (n = 18, 41.8%) Control group (n = 25, 58.2%) P
Cardiorespiratory parameters
    SBP (mm Hg) 111.66 ± 7.9 100.5 ± 8.5 0.001
    SBP centile 81.61 ± 17.7 52.8 ± 11.2 0.001
    DBP (mm Hg) 64.7 ± 9.1 57.7 ± 11.1 0.03
    DBP centile 66.3 ± 20.3 54.9 ± 13.8 0.05
    HR (bpm) 77.0 ± 9.0 67.5 ± 7.3 0.001
Autonomic cardiovascular tests
    Head-up tilt test
        ΔHR (bpm) 21.1 ± 12.2 20.6 ± 14.3 NS
        30:15 index 1.16 ± 0.13 1.25 ± 0.13 0.03
        ΔSBP (mm Hg) 12.8 ± 9.2 7.8 ± 7.7 0.05
        ΔDBP (mm Hg) 17.1 ± 10.3 9.0 ± 5.9 0.002
    Valsalva maneuver
        Valsalva ratio 1.5 ± 0.3 1.6 ± 0.3 NS
        ΔHR (max-min, bpm) 17.6 ± 9.6 13.7 ± 9.3 NS
    Deep breathing test
        E:I ratio 1.38 ± 0.2 1.5 ± 0.2 NS
        ΔHR (insp-exp, bpm) 9.0 ± 3.4 13.4 ± 5.9 0.006

SBP, systolic blood pressure (mm Hg); DBP, diastolic blood pressure (mm Hg); HR, heart rate (bpm); ΔHR, highest and lowest heart rate changes during first 30 sec in orthostatic position (bpm); 30:15 index, RR interval at 15th and at 30th beats after tilt (normal value > 1.04); ΔSBP and ΔDBP (mm Hg), diastolic and systolic blood pressure changes during first 3 min of test; Valsalva ratio, the longest RR interval after manoeuvres and the shortest RR interval during manoeuvres (normal value more than 1.21); ΔHR (max-min, bpm), the greatest heart rate difference from baseline during Valsalva maneuver; E:I ratio, the longer RR interval during expiratory phase and the shorter RR interval during inspiratory phase (normal value more than 1.10); ΔHR (insp-exp, bpm), the mean difference between highest and lowest heart rate in each respiratory cycle (normal value > 15 bpm).