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. 2010 Oct 1;33(10):1373–1380. doi: 10.1093/sleep/33.10.1373

Table 2.

Characteristics of studies that evaluated timing of driving improvement following CPAP

Year No. of Individuals in study (n = ) Study design Age Distribution AHI (SD) Mean BMI (SD) Mean ESS (SD) % Male Factors controlled for (if compared to controls) Relevant outcomes reported
Loredo et al.36 2006 CPAP: 22 Randomized, double-blind, placebo-controlled, parallel trial CPAP: 48.2 ± 10.9 65.9 ± 28.6 31.8 ± 5.5 11.6 ± 4.9 82 Daily average treatment duration Sleepiness
Placebo:19 Placebo: 48.3 ± 11.2 57.5 ± 32.1 31.8 ± 6.8 12.3 ± 6.7 84
Oxygen:22 Oxygen: 43.4 ± 8.6 64.9 ± 33.7 32.0 ± 6.4 12.8 ± 4.5 73
Orth et al.37 2005 31 Prospective case series 55.3 ± 10.2 NR NR NR 100 NA Simulated driving, sleepiness
Turkington et al.38 2004 CPAP:18 Controlled trial CPAP: 49.9 ± 10 NR 39 ± 7.7 Median: 15.5 94 Age, gender, RDI, BMI, ESS Simulated driving, sleepiness
Control:18 Control: 51.7 ± 12.2 36.6 ± 5.3 Median: 16 94
Wiest et al.39 2002 44 Randomized, cross-over trial 54.1 ± 9.7 53.6 ± 20.4 32.9 ± 5.3 14.9 ± 4.8 80 NA Sleepiness
Ficker et al.40 2000 18 Randomized, cross-over trial 50.6 ± 10.5 48.0 ± 28.1 NR 13.3 ± 3.0 100 NA Sleepiness
Saletu et al.41 1999 13 Randomized, cross-over trial 58.1 ± 8.7 29.1 ± 13.0 NR NR 100 NA Sleepiness