Table 3. Interactions observed between protein and RNA and within RNA.
Residue/Base* or Base/Base* | Between atoms | Bond type | Distance (Å) |
Lys14/G0 | NZ/2′-OH | Hydrogen bond | 3.3/3.2 |
Leu17/G0 | O/N2 | Hydrogen bond | 3.0/2.9 |
Asn18/A1 | O/N1 | Hydrogen bond | 2.9/2.7 |
Asn18/G0 | OD/2′OH | Hydrogen bond | 2.6/2.7 |
Leu20/G0 | O/N2 | Hydrogen bond | 2.4/2.5 |
Phe25/G0 | Aromatic ring | Aromatic stacking | - |
Pro152/A1 | Pro152 ring and A1 ribose | Van der Waals | 3.6/3.7 |
G2/G8 | O6/N2 | Hydrogen bond | 2.7 |
G2/G8 | N7/N1 | Hydrogen bond | 2.9 |
G2/A4′ | O2/N1 | Hydrogen bond | 3.3 |
A4/U7′ | N6/O4 | Hydrogen bond | 2.4 |
Interactions between the MTase and the RNA octamer. Also listed the intramolecular RNA interactions. Primed numbers indicate residues related by the 2-fold ncs axis.