Table 1.
Lytic and latent KSHV antibody levels and Odds Ratios (OR's) for seropositivity by municipal region, HIV and syphilis status and education
| Lytic K8.1 | Latent Orf 73 | |||||||
| Total (n) | Age Mean (± SD) | Total Positive (n) (% Positive) | Antibody level μg(SD range) | Adjusted OR (95%CI) | Total Positive (n) | Antibody level μg(SD range)* | Adjusted OR (95%CI) | |
| All Subjects | 1740 | 26.0(6.2) | 568(32.6) | 0.77(0.31 -1.38) | - | 568(32.6) | 0.40(0.11-0.76) | - |
| Municipality Region | ||||||||
| Soweto | 293 | 24.9(5.8)ab | 76(25.9) | 0.71(0.27-1.29)b | 1 | 79(27.0) | 0.37(0.09-0.73) | 1 |
| Ekurhuleni | 567 | 26.5(6.3)a | 204(36.0) | 0.79(0.30 - 1.46) | 1.7(1.2 - 2.3)* | 195(34.4) | 0.40(0.11-0.77) | 1.5(1.0 - 2.1) |
| Emfuleni | 330 | 25.9(6.3) | 107(32.4) | 0.75(0.32-1.32) | 1.5(1.0 - 2.1)* | 118(35.8) | 0.40(0.13-0.74) | 1.7(1.2 - 2.4)* |
| Tshwane | 207 | 25.8(6.1) | 53(25.6) | 0.71(0.32 -1.21)a | 1.1(0.7 - 1.7) | 52(25.1) | 0.36(0.10-0.68) | 1.0(0.7 - 1.6) |
| West Rand | 343 | 26.4 (6.1)b | 128(37.3) | 0.84(0.37-1.49)ab | 1.6(1.1 - 2.3)* | 124(36.2) | 0.43(0.13-0.82) | 1.5(1.0 - 2.2) * |
| P4df | 0.0063 | 0.0069 | 0.0233 | 0.0675 | 0.0185 | |||
| Education Level | ||||||||
| < 2 years | 117 | 28.5 (7.9)a | 46(39.3) | 0.90(1.67-0.35)a | 1 | 47(40.2) | 0.45(0.12-0.90) | 1 |
| 2 - 5 years | 513 | 26.5 (6.8)b | 193(37.6) | 0.82(0.32-1.48)b | 0.8 (0.5 - 1.2) | 176(34.3) | 0.40(0.11-0.85) | 0.6(0.4 - 1.0) |
| 6 - 12 years | 119 | 26.4 (5.6) | 35(29.4) | 0.75(0.30-1.36) | 0.4(0.3 - 0.8)* | 37(31.1) | 0.42(0.14-0.80) | 0.5(0.3 - 0.9) * |
| Post Matric | 959 | 25.4 (5.5)ab | 286(29.8) | 0.73(0.31-1.30)ab | 0.6(0.4 - 0.8)* | 300(31.3) | 0.42(0.11-0.72) | 0.6(0.4 - 0.9) * |
| P3df | 0.042 | 0.0019 | 0.002 | 0.0874 | 0.0426 | |||
| HIV Infection | ||||||||
| Negative | 1338 | 26.2 (6.4) | 345(25.8) | 0.70(0.28-1.27) | 1 | 341(25.5) | 0.36(0.09-0.68) | 1 |
| Positive | 402 | 25.3 (5.4) | 223(55.5) | 1.00(0.50-1.69) | 3.7(2.9 - 4.7) * | 227(56.5) | 0.54(0.21-0.98) | 3.8(3.0 - 4.8) * |
| P1df | 0.011 | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | |||
| Syphilis Infection | ||||||||
| Negative | 1442 | 25.9 (6.2) | 461(32.0) | 0.77(0.31-1.38) | 1 | 454(31.5) | 0.39(0.10-0.75) | 1 |
| Positive | 298 | 26.4 (5.8) | 107(35.9) | 0.79(0.34-1.38) | 1.0 (0.7 - 1.3) | 114(38.3) | 0.43(0.15-0.81) | 1.2 (0.9 - 1.6) |
| P1df | 0.24 | 0.55 | 0.8924 | 0.087 | 0.2395 | |||
#μg(SD range) geometric mean and standard deviation range. Means with the same letter are significantly different (p, 0.05). * Statistically significant Odds Ratios.