Table 2.
Minimal inhibitory concentrations in μg/ml of drugs tested against E. spinifera. MIC listed is the geometric mean of multiple strains tested in each reference.
Ref | ITZ | VCZ | FCZ | TBF | 5-FC | AMB | POS |
---|---|---|---|---|---|---|---|
7* | 0.03 | 0.125 | nd | nd | nd | 0.5 | <0.015 |
8 | 0.05 | 0.3 | 55.05 | 0.26 | 3.44 | 0.7 | nd |
32† | 0.06 | 0.27 | 45.25 | 0.3 | 5.66 | 0.92 | nd |
Abbreviations: ITZ – itraconazole, VCZ – voriconazole, FCZ – fluconazole, TBF – terbinafine, 5-FC – 5 fluorocytosine, AMB – amphotericin B, POS – posaconazole, nd – not done.
This reference determined MIC50 and MIC90. The MIC listed is for MIC50, consistent with the other references.
This reference tested susceptibility of environmental and clinical strains at various temperatures. The MIC listed is for clinical isolates grown at 35°C, consistent with the other references.