Table 4.
Association of MBL Haplotypes with Leprosy and Leprosy Reactions
| MBL1 Haplotypes | Leprosy | OR | 2P | Leprosy Class | OR | 2P | Reversal reaction | OR | 2P | ENL | OR | 2P | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No (f) | Yes (f) | TT+BT (f) | BB+BL+LL (f) | No (f) | Yes (f) | No (f) | Yes (f) | |||||||||
| CGG | 164.3 (0.85) | 1420.1 (0.82) | 525.7 (0.82) | 881.0 (0.82) | 1048.3 (0.82) | 371.2 (0.82) | 653.2 (0.83) | 186.6 (0.80) | ||||||||
| CAG | 18.7 (0.05) | 218.8 (0.06) | 1.35 (0.82–2.23) | 0.235 | 86.9 (0.07) | 130.5 (0.06) | 0.90 (0.67–1.20) | 0.464 | 161.7 (0.06) | 57.8 (0.06) | 1.01 (0.73–1.39) | 1.009 | 89.8 (0.06) | 34.8 (0.07) | 1.36 (0.89–2.07) | 0.157 |
| TGG | 7.7 (0.04) | 56.9 (0.03) | 0.85 (0.39–1.84) | 0.682 | 14.3 (0.02) | 42.0 (0.04) | 1.75 (0.95–3.21) | 0.069 | 44.7 (0.03) | 12.8 (0.03) | 0.81 (0.43–1.52) | 0.808 | 29.8 (0.04) | 8.4 (0.04) | 0.98 (0.45–2.15) | 0.967 |
| CGA | 3.0 (0.02) | 24.1 (0.01) | 0.93 (0.28–3.12) | 0.906 | 9.5 (0.01) | 14.5 (0.01) | 0.91 (0.40–2.08) | 0.826 | 18.0 (0.01) | 6.0 (0.01) | 0.94 (0.37–2.39) | 0.943 | 9.0 (0.01) | 3.6 (0.02) | 1.39 (0.40–4.78) | 0.602 |
| CAA | 0.0 (0.00) | 6.0 (0.00) | NA | 0.405 | 5.0 (0.01) | 1.0 (0.00) | 0.12 (0.01–1.02) | 0.020 | 4.0 (0.00) | 2.0 (0.00) | 1.41 (0.26–7.74) | 1.412 | 1.0 (0.00) | 0.0 (0.00) | 0.00 (0.01–61.37) | 0.593 |
1
Order for 3 MBL haplotypes, left to right: C154T, G161A, G170A
2
P value represents the comparison of a given haplotype with reference to haplotype CGG. P values <0.05 are in bold
NA, not available.