Effect of Passiflora extracts on CF-1 mice in the elevated plus maze. A, percent time spent in the open arms (time spent in open arms/(time spent in open + closed arms). B, Extending over edges of the open arms. C, ratio of entries into open arms over entries into open + closed arms. D, distance moved in the open arms. Means and standard errors are shown, *p < 0.05 versus control, **p < 0.01 versus control, ***p < 0.001 versus control, one-way ANOVA followed by Dunnet’s posthoc test, two-tailed. All extracts show anxiogenic effects in one or more measures of anxiety.