Figure 5.
fMRI activation patterns as a function of stimulus spatial frequency and contrast in individuals with schizophrenia (Scz) and controls (Ctl). A. Stimulus used for activation. B. Relative activation as function of spatial frequency (coded by color) shown on unfolded occipital cut. Note reduction in low spatial frequency (red regions) in Scz relative to Ctl, particularly at low contrast, which biases activity toward magnocellular processing. C. Plots of activation densities as a function of spatial frequency for high and low contrast stimuli in Scz vs. Ctl, showing reduced low spatial frequency response. From [122].