Table 1. Ranking of BLM peptides potentially phosphorylated by Chk1 as obtained by in silico analysis.

The residue based statistical pair potential scores, and all atom binding energies for the peptides are listed. The peptides are ranked based on their residue based statistical pair potential scores. The rows for the 6 peptides that lie in 1 to 660 amino acid region of BLM protein are highlighted in pink. VDW represents the contribution due to van der Waals interaction while ELE represents the contribution due to electrostatic interaction.

Serial number	Ser/Thr position	Peptide sequence	Residue based statistical pair potential scores (BT)	Binding energy calculated using Insight II (Kcal mol−1)
				VDW	ELE	TOTAL
1	Ser646		−7.72	−68.724	−36.337	−105.061
2	Ser729		−5.26	−56.895	−26.337	−83.232
3	Thr581		−5.03	−55.567	−34.583	−90.15
4	Ser1361		−4.81	−43.757	−26.804	−70.561
5	Ser1375		−3.79	−53.314	−35.054	−88.368
6	Ser434		−3.22	−57.886	−39.371	−97.257
7	Thr1350		−3.01	−55.531	−41.978	−97.509
8	Ser367		−2.72	−66.311	−43.226	−109.537
9	Ser602		−2.4	−52.816	−41.17	−93.986
10	Thr182		−2.08	−53.744	−29.651	−83.395