Table 3.
Multidrug resistance protein | n | - | + | ++ | +++ | Strongly positive rate(%) |
---|---|---|---|---|---|---|
P-gp | 30 | 3 | 13 | 10 | 4 | 46.67 |
Topo II | 30 | 21 | 3 | 2 | 4 | 20.00 |
GST-π | 30 | 13 | 14 | 2 | 1 | 10.00 |
MRP | 30 | 24 | 4 | 1 | 1 | 6.67 |
LRP | 30 | 22 | 6 | 1 | 1 | 6.67 |
The expression of resistance proteins in interstitial cells are similar to the tumor cells. The positive expression of P-gp is highest, the difference was statistically significant (Rank sum test, P < 0.05)