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. 2010 Sep 5;29(1):122. doi: 10.1186/1756-9966-29-122

Table 3.

Expression of the 5 multidrug resistance proteins in the interstitial cells

Multidrug resistance protein n - + ++ +++ Strongly positive rate(%)
P-gp 30 3 13 10 4 46.67
Topo II 30 21 3 2 4 20.00
GST-π 30 13 14 2 1 10.00
MRP 30 24 4 1 1 6.67
LRP 30 22 6 1 1 6.67

The expression of resistance proteins in interstitial cells are similar to the tumor cells. The positive expression of P-gp is highest, the difference was statistically significant (Rank sum test, P < 0.05)