Table 2.
Genes containing normal (N) or tumor (T)-specific cassette exons predicted in silico
| Gene | Tissue(s) | Cassette Exon(s) | Description |
|---|---|---|---|
| ACTN1 | CNS | N | actinin, alpha 1 |
| ALDOA | TES | N | aldolase A, fructose-bisphosphate |
| ATP6V0A1 | CNS | N | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| CS | CNS | T | citrate synthase |
| CTNNA1 | CNS | N | catenin (cadherin-associated protein), alpha 1, 102kDa |
| DCTN1 | CNS | N/T | dynactin 1 (p150, glued homolog, Drosophila) |
| EEF1D | EYE | T | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EWSR1 | CNS | N | Ewing sarcoma breakpoint region 1 |
| FAM104A | TES | N | family with sequence similarity 104, member A |
| FAM49B | CNS | N | family with sequence similarity 49, member B |
| GSN | KID | T | gelsolin (amyloidosis, Finnish type) |
| HDLBP | CNS | T | high density lipoprotein binding protein |
| HLA-B | RES, LYM, MSK | N/T | major histocompatibility complex, class I, B |
| HLA-C | LYM, MSK, DER | N/T | major histocompatibility complex, class I, C |
| HLA-DRB1 | CNS | T | major histocompatibility complex, class II, DR beta 1 |
| HSPA8 | DER | T | heat shock 70 kDa protein 8 |
| IARS | CNS | N | isoleucyl-tRNA synthetase |
| IDH3A | LYM | N | isocitrate dehydrogenase 3 (NAD+) alpha |
| ITIH4 | LIV | N | inter-alpha (globulin) inhibitor H4 |
| LDHA | DER | N | lactate dehydrogenase A |
| LMNA | DER | T | lamin A/C |
| METT10D | CNS | T | methyltransferase 10 domain containing protein |
| MYL6 | PLA | N | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| MVK | CNS | N | mevalonate kinase |
| NAP1L1 | MSK | T | nucleosome assembly protein 1-like 1 |
| NDRG4 | CNS | N | N-myc downstream regulated gene family member 4 |
| NRSN2 | CNS | N | neurensin 2 |
| PCNP | CNS | N | PEST proteolytic signal containing nuclear protein |
| PKM2 | TES | N | pyruvate kinase, muscle |
| PLEKHB1 | EYE | N | pleckstrin homology domain containing, family B member 1 |
| POMT1 | TES | T | protein-O-mannosyltransferase 1 |
| PRKCZ | PLA | T | protein kinase C, zeta |
| RAN | RES | T | RAN, member RAS oncogene family |
| RPH3A | CNS | N | rabphilin 3A homolog (mouse) |
| RPS24 | MSK | N | ribosomal protein S24 |
| SELENBP1 | CNS | N | selenium binding protein 1 |
| SLC25A3 | MSK | N/T | solute carrier family 25 (mitochondrial phosphate carrier), member 3 |
| STRADA | CNS | N | STE20-related kinase adaptor alpha |
| TMEM87A | CNS | N | transmembrane protein 87A |
| TPD52L2 | MSK | N | tumor protein D52-like 2 |
| TPM3 | MSK | N | tropomyosin 3 |
| UQCC | CNS | N | ubiquinol-cytochrome c reductase complex chaperone |
| WARS | LYM | T | tryptophanyl-tRNA synthetase |
| YPEL5 | CNS | T | yippee-like 5 (Drosophila) |
| ZFAND6 | TES | N | zinc finger, AN1-type domain 6 |
| ZNF655 | CNS | T | zinc finger protein 655 |