Figure 3. CT scan of a 12-year-old patient with Ewing’s sarcoma, at baseline and after six cycles of treatment (A), and a 24-year-old patient with Ewing’s sarcoma with ongoing partial response (B).
In A, target lesion decreased by about 60% after six cycles, with a remaining central calcification. The residual mass was resected and confirmed as a pathological complete response. Non-target lesions also disappeared. In B, several target lung nodules disappeared after four cycles of treatment, qualifying for partial response. The non-target lesion in the mediastinum decreased by 60% (this also followed 45 Gy of radiation therapy in 15 fractions).