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. Author manuscript; available in PMC: 2010 Sep 20.
Published in final edited form as: Cancer Res. 2005 Sep 15;65(18):8286–8297. doi: 10.1158/0008-5472.CAN-04-1913

Figure 3.

Figure 3

TRAIL-induced changes in NAO staining are not dependent on caspase activation. A, z-VAD does not inhibit TRAIL-induced changes in NAO staining: Flow cytometry of NAO fluorescence for Jurkat cells, which were preincubated with 100 μmol/L Z-VAD-FMK for 30 minutes followed by TRAIL (10 ng/mL) treatment for 1 hour as in Fig. 1. Data obtained in the presence of z-VAD alone were superimposable to those of the control sample (data not shown). B, pro-caspase-8 is not processed significantly after 1-hour TRAIL treatment under the same conditions as in (A).