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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Exp Eye Res. 2010 Jul 1;91(3):425–432. doi: 10.1016/j.exer.2010.06.017

Figure 5. BzATP kills retinal ganglion cell in adult retinas.

Figure 5

A) The mean ganglion cell numbers in each of six regions from the inferior, nasal, superior and temporal quadrants following injection of control saline (white bars) or 250 μM BzATP (black bars) into the vitreal chamber of contralateral eyes from adult rats. Injection of BzATP reduced the number of ganglion cells, particularly in the nasal quadrant. n=6 rats.

B) Mean number of ganglion cells per quadrant following injection of control saline or 250 μM BzATP. BzATP significantly reduced the number of ganglion cells in the nasal, superior and temporal quadrants. (* p<0.05; paired t-test; n=36 corresponding regions from 6 adult rats).

C) Representative image from peripheral nasal region of adult eye injected with saline.

D) Corresponding region from contralateral eye injected with BzATP. In panels C and D, bar = 50 μm.