Table 3.
Cost parameters
| Model parameters | Costs | Source |
|---|---|---|
| Tamoxifen 20 mg | 54.31 € | Red Book [25] |
| Exemestan 25 mg | 1005.34 € | Red Book [25] |
| Osteoporosis | ||
| Osteoporosis pharmaceuticals | 210.12 € | Red Book [25] |
| Osteoporosis fracture | 2878.72 € | DRG Browser V2005 [23] |
| Thromboembolism | ||
| Costs of the initial episode | 3239.66 € | DRG Browser V2005 [23] |
| Running costs for the first model cycle after incidence | 93.28 € | EBM 2000 plus [24], Red Book [25] |
| Following cycles up to 3 years after incidence | 62.47 € | EBM 2000 plus [24], Red Book [25] |
| Endometrial cancer | ||
| Diagnosis (once) | 21.42 € | EBM 2000 plus [24] |
| Operation (with radiotherapy) (once) | 5692.97 € | DRG Browser V2005 [23] |
| Chemotherapy (1. regime) | 3201.36 € | Red Book [25] |
| Breast cancer therapy | ||
| Operation cost (either breast ablation or preservation) (once) | 4188.12 € | DRG Browser V2005 [23] |
| Chemotherapy (1. regime responders) | 3201.36 € | Red Book [25] |
| Chemotherapy (1. regime non-responders/3 months of treatment) | 1600.68 € | Red Book [25] |
| Chemotherapy (2. regime) | 11,053.95 € | Red Book [25] |
| Terminal care | ||
| Medical home care or nursing home (14 days) | 460.53 € | EBM 2000 plus [24] |
| At hospital or hospice (14 days) | 3609.53 € | DRG Browser V2005 [23] |
| Weighted average costs | 2223.97 € | |
| Routine care if well (5 years of treatment) | ||
| Home visit by the doctor (twice per year with 20.40 € each) | 204.00 € | EBM 2000 plus [24] |
| GP visit (4 × per year with 11.48 € each) | 229.50 € | EBM 2000 plus [24] |
| Cardiac failure | ||
| GP visit | 11.48 € | EBM 2000 plus [24] |
| Cardiology outpatients | 75.74 € | EBM 2000 plus [24] |
| ECG | 0.00 € | EBM 2000 plus [24] |
| Mammogram | 36.72 € | EBM 2000 plus [24] |
| Phlebotomy | 0.00 € | EBM 2000 plus [24] |
| Biochemistry | 7.20 € | EBM 2000 plus [24] |
| Haematology | 1.10 € | EBM 2000 plus [24] |
| Spirometry | 57.12 € | EBM 2000 plus [24] |
| ECHO | 0.00 € | EBM 2000 plus [24] |
| Frusemide | 25.58 € | Red Book [25] |
| Carvedolol | 217.94 € | Red Book [25] |
| Enalapril | 44.64 € | Red Book [25] |
| Lisinopril | 42.86 € | Red Book [25] |
| Influenza vaccine | 24.07 € | Red Book [25]; own calculation |
| Pneumococcal vaccine (once) | 41.97 € | Red Book [25]; own calculation |
| Total cost of cardiac failure | 421.65 € | |
| Hypertension | ||
| GP visit | 22.95 € | EBM 2000 plus [24] |
| Bendrofluazide 2.5 mg | 51.14 € | Red Book [25] |
| Enalapril | 44.64 € | Red Book [25] |
| Lisinopril | 42.86 € | Red Book [25] |
| Atenolol | 34.07 € | Red Book [25] |
| Amlodipine | 37.57 € | Red Book [25] |
| Nifedipine XL | 43.09 € | Red Book [25] |
| Losartan | 178.35 € | Red Book [25] |
| Valsarían | 77.30 € | Red Book [25] |
| Total cost of hypertension | 151.38 € | Red Book [25] |
| Arthr algia | ||
| GP visit | 11.48 € | EBM 2000 plus [24] |
| Paracetamol | 82.22 € | Red Book [25] |
| Naproxen | 56.56 € | Red Book [25] |
| Diclofenac | 26.57 € | Red Book [25] |
| Total cost of arthralgia | 66.66 € | |
| Vaginal haemorrhage | ||
| Hysteroscopy und biopsy | 683.40 € | KBV EBM 2000 plus |
| Ultrasound | 19.38 € | KBV EBM 2000 plus |
| Histology | 26.27 € | KBV EBM 2000 plus |
| Total cost of vaginal haemorrhage | 729.05 € | |
| Myocardial ischaemia | ||
| GP visit | 11.48 € | EBM 2000 plus [24] |
| Outpatient visit cardiology | 75.74 € | EBM 2000 plus [24] |
| ECG | 0.00 € | EBM 2000 plus [24] |
| Phlebotomy | 0.00 € | EBM 2000 plus [24] |
| Biochemistry | 7.20 € | EBM 2000 plus [24] |
| Exercise tolerance test | 27.80 € | EBM 2000 plus [24] |
| GTN spray | 63.72 € | Red Book [25] |
| Atenolol | 34.07 € | Red Book [25] |
| Isosorbide mononitrate | 21.40 € | Red Book [25] |
| Total cost of myocardial ischaemia | 248.40 € |
ECG = Electrocardiogram, ECHO = echocardiography, GTN = glyceryl trinitrate.