Table 2.
Characteristics of 124 acute erythroid leukemia cases at the time of diagnosis
| Characteristic | Findings in acute erythroid leukemia cases |
|---|---|
| Sex, M/F | 88/36 (ratio: 2.4:1) |
| Median age, y (range) | 64 (12-93) |
| Median hemoglobin level, g/L | 90 |
| Patients with hemoglobin level less than 100 g/L, n (%) | 88/119 (74) |
| Median platelet count, ×109/L | 47 |
| Patients with platelet count less than 100 × 109/L, n (%) | 92/118 (78) |
| Median absolute neutrophil count, ×109/L | 0.8 |
| Patients with absolute neutrophil count less than 1.8 × 109/L, n (%) | 91/118 (77) |
| Median red cell mean corpuscular volume, fL | 92 |
| Median reticulocyte count | 0.024 |
| Patients with peripheral nucleated red blood cells, n (%) | 38/53 (72) |
| Median peripheral nucleated red blood cells/100 white blood cells (range) | 5 (1-302) |
| Patients with peripheral blasts, n (%) | 58/118 (49) |
| Median peripheral blasts, percentage (range) | 4 (1-19) |
| Median bone marrow cellularity, percentage (range) | 80 (5-100) |
| Median bone marrow aspirate erythroid percentage (range) | 62 (51-88) |
| Median bone marrow myeloblast percentage of all nucleated cells (range) | 12 (4-19) |
| Median bone marrow myeloblast percentage of nonerythroid cells (range) | 32 (20-58) |
| Erythroid dysplasia, patients with finding, n (%) | 110/113 (97) |
| Myeloid dysplasia, patients with finding, n (%) | 57/113 (50) |
| Megakaryocytic dysplasia, patients with finding, n (%) | 80/113 (71) |
| Ring sideroblasts, patients with finding, n (%) | 23/110 (21) |
| Cytogenetic findings in 119 cases, no. of patients (%) | |
| Normal karyotype | 32 (27) |
| Complex karyotype | 53 (45) |
| 3 abnormalities | 3 (3) |
| 4 abnormalities | 7 (6) |
| 5 or more abnormalities | 43 (36) |