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. Author manuscript; available in PMC: 2010 Sep 20.
Published in final edited form as: J Immunol. 2010 Jul 19;185(4):2570–2579. doi: 10.4049/jimmunol.1000644

Figure 1. Arthritis score in mice varying in hTNFα and SphK1 status.

Figure 1

7 month old littermates of hTNF/SphK1-/-show decreased severity and progression of arthritis. Less disease noted in the hTNF/SphK1-/- mice compared to hTNF/SphK1+/+ mice (A). Observed arthritis scores in groups varying in SphK1 and TNFα genotype from 3 months to 6 months of age (B). Decreased severity and disease progression is observed in hTNF/SphK1-/- mice compared to hTNF/SphK1+/+ mice. Data are presented as mean +/- SEM, n>16 mice/group, p< 0.05, 0.01 by ANOVA.