Table 1.
Biochemical Pathways | Encephalitozoon cuniculi | Antonospora locustae | Octosporea bayeri | Nosema ceranae | Enterocytozoon bieneusi | |
Genomic data available | Sanger (complete) | Sanger | Solexa | 454 | Sanger | 454 |
Estimated genome size (Mb) | 2.9 | 5.6 | ≤24.2 | ≤10 | 6 | |
(A) Pathways with strong differences among species | ||||||
Glycolysis | 12 | 12 | 12 | 12 | 1 | 1 |
Pentose phosphate pathway | 5 | 5 | 5 | 5 | 1 | 1 |
Trehalose metabolism | 4 | 4 | 4 | 4 | 0 | 0 |
Fatty acids biosynthesis | 20 | 19 | 20 | 19 | 5 | 6 |
Number of ORFs | 41 | 40 | 41 | 40 | 7 | 8 |
(B) Pathways present in all species | ||||||
Transcriptional control | 44 | 41 | 44 | 34 | 39 | 39 |
60S ribosomal proteins | 46 | 39 | 39 | 39 | 45 | 43 |
40S ribosomal proteins | 31 | 31 | 29 | 25 | 26 | 27 |
tRNA synthetases | 21 | 21 | 21 | 21 | 21 | 21 |
rRNA processing | 20 | 20 | 18 | 19 | 18 | 18 |
Recombination and DNA repair | 22 | 20 | 21 | 20 | 19 | 19 |
Meiosis | 18 | 18 | 15 | 18 | 14 | 13 |
Protein kinases | 19 | 18 | 14 | 17 | 18 | 19 |
Transcription initiation factors | 18 | 18 | 18 | 15 | 17 | 17 |
Cell growth and cell polarity | 11 | 8 | 9 | 10 | 10 | 9 |
Deoxyribonucleotide metabolism | 11 | 6 | 7 | 4 | 11 | 10 |
C-compound and carbohydrate metabolism | 9 | 9 | 9 | 8 | 7 | 7 |
DNA-directed DNA polymerases | 8 | 8 | 8 | 8 | 8 | 8 |
DNA replication factors A and C | 8 | 7 | 6 | 5 | 8 | 8 |
DNA replication licensing factors, MCM family | 8 | 8 | 8 | 8 | 8 | 8 |
tRNA modification | 7 | 7 | 7 | 6 | 7 | 7 |
tRNA synthesis | 7 | 7 | 7 | 6 | 6 | 6 |
DNA-dependent helicases, ligases, telomerases | 7 | 7 | 7 | 7 | 7 | 7 |
Chromosome segregation proteins, SMC family | 5 | 5 | 5 | 5 | 5 | 5 |
Phosphate metabolism | 5 | 3 | 5 | 5 | 5 | 5 |
Amino acid metabolism | 4 | 4 | 3 | 4 | 3 | 3 |
Transcription elongation factors | 3 | 3 | 2 | 3 | 3 | 3 |
DNA topoisomerases | 3 | 3 | 3 | 2 | 3 | 3 |
Nitrogen and sulfur metabolism | 3 | 3 | 3 | 2 | 2 | 2 |
Polynucleotide degradation | 2 | 2 | 2 | 2 | 2 | 2 |
tRNA processing | 2 | 2 | 2 | 1 | 2 | 2 |
Origin recognition complex | 2 | 2 | 2 | 1 | 2 | 2 |
Glycerol phosphate shuttle | 2 | 2 | 2 | 2 | 1 | 1 |
Sugar transporters | 3 | 2 | 2 | 3 | 3 | 3 |
ADP/ATP transporters | 4 | 3 | 1 | 4 | 4 | 4 |
Number of ORFs | 353 | 327 | 319 | 304 | 324 | 321 |
Total ORFs | 394 | 367 | 360 | 344 | 331 | 329 |
MCM, minichromosome maintenance; ORF, open reading frame; rRNA, ribosomal RNA; SMC, structural maintenance of chromosomes; tRNA, transfer RNA.