Table II.

Reciprocal 50% neutralization titres (NT₅₀) of sera from rabbits boosted with the short V3-CTB construct (rabbits 1–5) or the full-length V3-CTB construct (rabbits 6–10). Pseudoviruses tested include the wild type SF162 and chimeric pseudoviruses carrying V3 sequences corresponding to the consensus sequences of clades B, F, A1, AE, AG, H and C.

DNA Prime	Protein Boost	Rabbit #	SF162wt	B	F	A/E	A1	AG	H	C
JR-FL gp120	Short V3-CTB	1	<10	316	<10	<10	<10	<10	<10	<10
		2	<10	332	<10	<10	21	<10	<10	<10
		3	<10	410	<10	<10	<10	<10	<10	<10
		4	<10	1,638	<10	16	31	<10	<10	<10
		5	<10	512	<10	<10	<10	<10	<10	<10
JRFL gp120	Full-length V3-CTB	6	<10	24,970	34	56	32	<10	<10	<10
		7	516	64,250	820	159	620	1,022	17	209
		8	495	37,987	613	648	296	190	24	67
		9	222	8,521	124	33	130	53	10	22
		10	510	50,912	1,022	559	686	317	111	104