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Reciprocal 50% neutralization titers (NT50) of sera from rabbits boosted with the full-length V3-CTB construct. Pseudoviruses tested include those from the standard multi-clade Tier 1 panel as well as a negative control psV carrying the envelope of murine leukemia virus (MuLV).
| Clade C | Clade B | Clade B | Clade B | ||
|---|---|---|---|---|---|
| Rabbit # | MW965.26 | Bx08.16 | BaL.26 | SS11961.1 | MuLV |
| 6 | 28 | 105 | 125 | 22 | <20 |
| 7 | 4,437 | 129 | 171 | 25 | <20 |
| 8 | 451 | 58 | 63 | <20 | <20 |
| 9 | 159 | 62 | 59 | <20 | <20 |
| 10 | 1,206 | 103 | 148 | <20 | <20 |
