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. Author manuscript; available in PMC: 2010 Sep 20.
Published in final edited form as: Neurotoxicol Teratol. 2009 Sep 6;32(2):142–151. doi: 10.1016/j.ntt.2009.08.011

Fig. 3.

Fig. 3

Arrows indicate the dose changes denoted as arrows 5–8 in Fig. 1 legend. A) Analysis of the means (±sem) of CPR PTC for weeks 23–66 revealed that the vehicle group completed more of the task than the high dose group on weeks indicated (*, p<0.05). There no differences between the vehicle and low dose groups. The low dose group completed more of the task than the high dose group when indicated (+, p<0.05). Note: For the CPR task the number of animals per group is 8 and not 10 due to the fact that data for only those subjects that had completed CPR training prior to dose escalation at week 23 were analyzed. B) Analysis of the means (±sem) of CPR RR for week's 23–66 revealed that the vehicle group responded faster than the high dose group during weeks indicated (*, p<0.05). There no differences between the vehicle and low dose groups. The low dose group responded faster than the high dose group when indicated (+, p<0.05). C) Analysis of the means (±sem) of CPR ACC for week's 23–66 revealed that the vehicle group performed better than the high dose group during weeks indicated (*, p<0.05). There was a significant difference between the vehicle and low dose group ACC during week 41 only (#, p<0.05). The low dose group performed better than the high dose group on weeks indicated (+, p<0.05).