Table 1.

EAE induction after intracerebral immunizations

Immunization	Incidence(%)	No.of mice	Meanday onseta	Meanmaximal scoreb
Intracerebral PBS + subcutaneous CFA-MOG	100	8 of 8	11.5 ± 1.2	2.26 ± 0.3
Intracerebral DCMOG + subcutaneous CFA-MOG	100	12 of 12	8.2 ± 1.0***c	2.62 ± 0.35*c
Intracerebral DCOVA + subcutaneous CFA-MOG	100	9 of 9	10.4 ± 0.5**d	2.6 ± 0.25*e
Intracerebral DCMOG + subcutaneous CFA	0	0 of 6

^aMean day of onset was calculated for the mice which developed EAE. Data represent mean ± SE.

^bMean maximal score was calculated for all mice in the group. Data represent mean ± SE.

^cp values of intracerebral DC_MOG compared with intracerebral PBS group.

^dp values of intracerebral DC_OVA compared with intracerebral DC_MOG.

^ep values of intracerebral DC_OVA compared with intracerebral PBS group.

*p < 0.05,

**p < 0.01,

***p < 0.001; Student's t test.