Figure 6. Leptin stimulates surfactant phospholipid synthesis by adult lung epithelial cells.
H441 adult lung epithelial cells were incubated with leptin for 24h and exposed to 3H-choline chloride for the last 4h. The H441 cell lamellar body fractions were subsequently assayed for 3H-saturated phosphatidylcholine content. Each bar represents the mean±standard deviation, n=5, *p< .05, **p< .01, control (C) versus leptin treated by analysis of variance.