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Proposed model of evolutionary events leading to obscurin-titin binding domain (OTBD) in present-day ankyrins. In vertebrates, successive duplications led to three different modules, I, II and III. Ank1 and Ank2 have all three modules, while Ank3 has only modules I and II. Adapted from Hopitzan et al. (2006). (permission has been obtained from Oxford University Press for the reproduction on this figure).
