Table 1.
Comparison of pncA sequencing, the pyrazinamidase assay, and the MGIT 960 system for PZA susceptibility testing.
|
M. tb strains (total no. of isolates) |
MGIT (S) PZase (pos) pncA (wt) |
MGIT (S) PZase (pos) pncA (mut) |
MGIT (R) PZase (neg) pncA (mut) |
MGIT (R) PZase (pos) pncA (wt) |
MGIT (R) PZase (pos) pncA (mut) |
|---|---|---|---|---|---|
| Susceptible (50) | 46 | 1 | - | 2 | 1 |
| MDR-TB (100) | 42 | 9 | 34 | 11 | 4 |
S; susceptible, R; resistant, PZase; pyrazinamidase assay, MGIT; BACTEC MGIT 960 method, pos; positive, neg; negative, wt; wild-type, mut; mutant