Figure 7.—

Mitotic loss of disomic chromosomes from spore JSC2-1-8c. The spore JSC2-1-8c was originally disomic for eight chromosomes (I, V-VII, IX, XI, XII, and XV). We examined 10 single-colony isolates of JSC2-1-8c (labeled 8c-1-10) by SPA, and found six genotypes (shown in solid-line depictions of yeast cells). In this figure, we show a pathway of chromosome loss consistent with these genotypes. The silhouette of a yeast cell with dashed lines is a hypothetical intermediate that was not detected. The numbers within each circle are the chromosome numbers, and the colors indicate the haploid from which the chromosome was derived.