Table 2.
Plasma bile acid levels and energy expenditure in patient groups with liver cirrhosis
| cirrhosis (all) (n = 46) |
cholestatic subgroup (n = 14) |
non-cholestatic subgroup (n = 14) |
normal value | |
|---|---|---|---|---|
| Total BA (μM) | 31.2 ± 3.3 | 40.5 ± 3.4 | 11.9 ± 1.5 | < 10 |
| CA (μM) | 10.3 ± 2.2 | 13.2 ± 0.7 | 4.2 ± 0.7# | <1.0 |
| CDCA (μM) | 13.7 ± 2.9 | 16.1 ± 4.3 | 6.7 ± 1.7# | <3.0 |
| DCA (μM) | 3.02 ± 1.48 | 5.81 ± 2.99 | 0.60 ± 0.16# | <1.0 |
| REE (kcal/d/1.73 m2) | 1716 ± 33 | 1676 ± 64 | 1650 ± 58 | |
| REE (kcal/d/kg FFM) | 36.9 ± 0.8 | 38.5 ± 1.9 | 37.9 ± 1.3 | |
| REE (% increase) | 18 ± 2 | 19 ± 4 | 18 ± 3 |
Data are given as means ± SEM. BA, bile acids; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; REE, resting energy expenditure; FFM, fat free mass. The percent increase in REE is the measured value related to the value predicted by use of the Harris-Benedict formula as described in the text. # Significantly different from the cholestatic subgroup as determined by Mann-Whitney U-test, at least P < 0.05.