Figure 6. Rosiglitazone attenuates GI candidiasis during type II diabetes.

(A) Blood glucose levels of mice fed a chow (NC) or a HFD after infection with C. albicans (50.10⁶ yeasts/mouse) and treatments with rosiglitazone (R) and WY14643 (WY) (n = 6). (B) Weight gain of these mice after infection with C. albicans. (C) C. albicans GI colonization of esophagus, stomach and cecum of mice fed a HFD and treated or not (HF C) with rosiglitazone (HF R) and WY14643 (HF WY) evaluated by RT-PCR. Data are represented as mean ± SEM *p<0.05 and **p<0.01 compared to NC control (NC C); #p<0.05 compared to HF control (HF C). The data are representative of three independent experiments.