Table 1.
Characteristics of study cohort
| Mobility Groups |
||||
|---|---|---|---|---|
| All (n=99) | Normal (n=33) | Intermediate (n=36) | Impaired (n=30) | |
| Subjects 75–79 years (F/M) | 29 (16/13) | 11 (6/5) | 11 (6/5) | 7 (4/3) |
| Subjects 80–84 years (F/M) | 38 (24/14) | 12 (8/4) | 13 (8/5) | 13 (8/5) |
| Subjects 85 years (F/M) | 32 (17/15) | 10 (5/5) | 12 (6/6) | 10 (6/4) |
|
| ||||
| Age (years) | 83 ± 4 | 82.0 ± 4.4 | 83.0 ± 3.9 | 83.3 ± 4.0 |
| Sex (F/M) | 57/42 | 19/14 | 20/16 | 18/12 |
| MMSE | 28.5 ± 1.3 | 28.7 ± 1.3 | 28.4 ± 1.4 | 28.3 ± 1.2 |
| BMI | 25.6 ± 3.9 | 24.3 ± 2.8 a | 25.3 ± 3.1 | 27.4 ± 5.1 |
| Subjects with hypertension | 71 (71%) | 22 (66%) | 26 (72%) | 23 (77%) |
| BPF | 0.704 ± 0.034 | 0.714 ± 0.038 b | 0.706 ± 0.034 | 0.692 ± 0.030 |
| WMF | 0.260 ± 0.057 | 0.270 ± 0.053 c | 0.270 ± 0.045 e | 0.235 ± 0.069 |
| GMF | 0.443 ± 0.051 | 0.442 ± 0.046 | 0.435 ± 0.047 | 0.455 ± 0.061 |
| WMHF | 0.010 ± 0.010 | 0.008 ± 0.008 d | 0.009 ± 0.006 | 0.013 ± 0.012 |
Brain volumes are expressed as fraction of ICC (mean: 1395 ± 138 mL, range: 1132–1780 mL). Significant difference with impaired group (Mann-Whitney):
a
p=0.008
b
p=0.017
c
p=0.034
d
p=0.040
e
p=0.049