Table 2.
Spearman correlation of global and regional WMH with mobility performance scores
| WMH Burden | Total SPPB Score | WS Score | CR Score | SB Score |
|---|---|---|---|---|
| rho (p) | rho (p) | rho (p) | rho (p) | |
| Total WMH | −0.223 (0.027) | −0.288 (0.004) | −0.191 (0.058) | −0.082 (0.422) |
| GCC-WMH | −0.266 (0.008) | −0.299 (0.003) | −0.259 (0.01) | −0.076 (0.454) |
| BCC-WMH | −0.212 (0.035) | −0.316 (0.001) | −0.209 (0.038) | 0.005 (0.959) |
| SCC-WMH | −0.391 (6×10−5) | −0.426 (10−5) | −0.345 (4×10−4) | −0.160 (0.114) |
| ACR-WMH | −0.247(0.014) | −0.296 (0.003) | −0.220 (0.029) | −0.119 (0.241) |
| SCR-WMH | −0.257 (0.010) | −0.339 (0.001) | −0.246 (0.014) | −0.075 (0.460) |
| PCR-WMH | −0.216 (0.032) | −0.279 (0.005) | −0.203 (0.044) | −0.016 (0.872) |
| ALIC-WMH | −0.294 (0.003) | −0.356 (0.0003) | −0.265(0.008) | −0.110 (0.280) |
| PLIC-WMH | −0.283 (0.004) | −0.343 (0.001) | −0.247 (0.014) | −0.093 (0.360) |
| CST-WMH | −0.268 (0.007) | −0.300 (0.003) | −0.238 (0.018) | −0.101 (0.320) |
| SLF-WMH | −0.157 (0.120) | −0.212 (0.035) | −0.208 (0.039) | 0.033 (0.749) |
Significant rho values are in bold, set at α≤ 0.05 for total WMH and at α≤0.005 for the ten ROIs (Bonferroni correction for multiple comparisons). Amount of WMH in SCC showed strongest and most significant correlation, particularly with the walking speed (WS) score.