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Increased COX-2, increased Bcl-xL, and decreased Bax levels in SUM149-CER variants. The cell lysates prepared from both the cell lines in normal growth conditions were subjected to western blot analysis as described in Materials and Methods. Two exposures of the Bcl-2 blot are shown- a light exposure (upper panel) identical to the Bcl-2 blot for BSC60 (Fig. 3A), and a longer exposure to visualize the weak Bcl-2 band (lower panel). SUM149, passage 24; SUM149-CER, passage 6.
