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. Author manuscript; available in PMC: 2011 Oct 5.
Published in final edited form as: Brain Res Rev. 2010 May 27;65(1):14–27. doi: 10.1016/j.brainresrev.2010.05.005

Table 2.

Cerebellar stimulation modulates nociception.

Stimulus Cerebellar site Effect Nociception Animal Paper
Electric Anterior lobe (intermediate part) Increased tail shock thresholds ↓ Squirrel Monkeys (Siegel and Wepsic, 1974)
Morphine Anterior (culmen region) Increased acute analgesia ↓ Rats (Dey and Ray, 1982)
Electric Lateral nucleus Modulated parafasicular neurons, Intralaminar thalamus ↑/↓ Rats (Liu et al., 1993)
Electric Posterior vermis (lobule VI) Increased midline neuron activity in lumbosacral spinal cord ↑ Rats (Saab and Willis, 2001)
DLH Posterior vermis (lobule VI) Increased midline neuron activity in lumbosacral spinal cord ↑ Rats (Saab and Willis, 2001)
DLH Cortex (vermis, lobule VIII) Increased nociceptive reflexes (abdominal) ↑ Rats (Saab and Willis, 2002)
DLH Fastigial nucleus Decreased nociceptive reflexes (abdominal) ↓ Rats (Saab and Willis, 2003)
*

DLH (D, L homocysteic acid) = nonspecific glutamate receptor agonist