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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Differentiation. 2010 Jul 17;80(2-3):147–154. doi: 10.1016/j.diff.2010.06.005

Figure 2. Functional relationships of miRNA target genes involved in the Wnt/β-catenin pathway predicted by using the Ingenuity Pathways software.

Figure 2

A) The genes potentially targeted by the miRNAs that were deregulated during Caco2-BBE cell differentiation (miR-125b, miR-146b-5p, miR-152, miR-424, miR-508-3p, miR-542-5p, miR-618, miR-552, miR-760 and miR-1268) were predicted to be involved in Wnt/β-catenin pathway. Potentially down- and up-regulated genes are presented in green and red, respectively. B) Real-time RT-PCR quantification of mRNA expression levels of miRNAs putative target genes. Values represent means ± S.E.M. of n = 6/condition. *P < 0.05; **P < 0.005; ***P < 0.001.