Table 2.

	No. of anti-Aβ seropositive mice	Antibody titers (µg/ml) mean±S.E.M.	Ig isotypes of Aβ42 antibodies
Week 7
AdPEDI-(Aβ1-6)₁₁ only	5/10	1.8±1.2	IgG1 >> IgG2a^a
AdPEDI-(Aβ1-6)₁₁ + simvastatin	9/10	1.9±0.7	IgG1 >> IgG2a^a
Week 10
AdPEDI-(Aβ1-6)₁₁ only	5/10	1.9±1.0	IgG1 >> IgG2a^a
AdPEDI-(Aβ1-6)₁₁ + simvastatin	7/10	2.3±0.9	IgG1 >> IgG2a^a
Week 13
AdPEDI-(Aβ1-6)₁₁ only	6/10	2.5±0.8	IgG1 >> IgG2a^a
AdPEDI-(Aβ1-6)₁₁ + simvastatin	6/10	8.8±2.4^b	IgG1 >> IgG2a^a

Characterization of anti-Aβ antibodies induced by AdPEDI-(Aβ1-6)₁₁ vaccination with or without simvastatin.

Levels of anti-Aβ IgG2a were less than the minimum detectable level by the isotype-specific ELISA.

P = 0.03.