Table 4. The association between quartiles of the Insall-Salvati Ratio and worsening PFJ cartilage damage and BMLs at follow-up.
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | p for trend | |
|---|---|---|---|---|---|
| ISR Range | 0.55-0.98 | 0.99-1.09 | 1.10-1.21 | 1.22-1.66 | |
| # of knees | 220 | 222 | 232 | 224 | |
| Lateral PFJ Cartilage Damage | |||||
| WORMS change ≥0.5 x/n (%) | 27/427 (6) |
24/420 (6) |
42/434 (10) |
49/379 (13) |
|
| Adjusted OR* (95% CI) |
1.0 (reference) |
0.9 (0.5, 1.6) |
1.5 (0.9, 2.5) |
2.1 (1.2, 3.5) |
0.0009 |
| Bone Marrow Lesions | |||||
| WORMS change ≥0.5 x/n (%) | 21/433 (5) |
34/434 (8) |
38/451 (8) |
47/427 (11) |
|
| Adjusted OR* (95% CI) |
1.0 (reference) |
1.6 (0.9, 3.0) |
1.7 (0.9, 3.2) |
2.3 (1.2, 4.3) |
0.0009 |
| Medial PFJ Cartilage Damage | |||||
| WORMS change ≥0.5 x/n (%) | 20/436 (5) |
36/424 (8) |
44/454 (10) |
40/432 (9) |
|
| Adjusted OR* (95% CI) |
1.0 (reference) |
1.9 (1.0, 3.4) |
2.1 (1.2, 3.7) |
2.0 (1.1, 3.6) |
0.005 |
| Bone Marrow Lesions | |||||
| WORMS change ≥0.5 x/n (%) | 14/436 (3) |
28/439 (6) |
26/461 (6) |
21/444 (5) |
|
| Adjusted OR* (95% CI) |
1.0 (reference) |
2.0 (1.0, 3.8) |
1.7 (0.9, 3.3) |
1.4 (0.7, 2.8) |
0.45 |
*
Adjusted for age, sex, and BMI